Topeka ? Some abortion opponents are upset that Sen. Sam Brownback is supporting Kansas Gov. Kathleen Sebelius’ nomination as U.S. secretary of health and human services.

Brownback, an anti-abortion Republican from Kansas, has had some of his strongest support from abortion opponents.

Meanwhile, Sebelius’ nomination by President Barack Obama, has been strongly criticized by anti-abortion groups. She supports abortion rights.

Operation Rescue President Troy Newman said Thursday that there is “profound disappointment” with Brownback’s decision. He said the Sebelius nomination has galvanized abortion foes.

Brownback has said he’s supporting Sebelius’ nomination despite their differences. He also has said it’s an honor for Kansas to have someone picked for the Cabinet.